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Publications
Engineering archaeal membrane-spanning lipid GDGT biosynthesis in bacteria: Implications for early life membrane transformations

mLife

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2025.03.13
Phylogeny-metabolism dual-directed single-cell genomics for dissecting and mining ecosystem function by FISH-scRACS-Seq

Innovation

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2025.01.02
Label-free prediction of tumor metastatic potential via ramanome

Small Methods

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2024.11.19
Ultrafast evolution of bacterial antimicrobial resistance by picoliter-scale centrifugal microfluidics

Anal Chem

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2024.11.12
Artificial intelligence-assisted automatic Raman-activated cell sorting (AI-RACS) system for mining specific functional microorganisms in the microbiome

Anal Chem

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2024.11.11
Rapid antimicrobial susceptibility test of Helicobacter pylori to metronidazole via single-cell Raman spectrometry

Helicobacter

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2024.09.16
Assessing the physiological properties of baker's yeast based on single-cell Raman spectrum technology

Synth Syst Biotechnol

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2024.09.11
Nature-inspired fungal fusarinine C-powered dual-mode fluorometric/colorimetric biosensing of fecal Helicobacter pylori with high-reliability

Sens Acutuators B-Chem

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2024.04.16
Rapid identification of lactic acid bacteria at species/subspecies level via ensemble learning of Ramanomes

Front Microbiol

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2024.04.08
Magnetic nanoparticle-mediated enrichment technology combined with microfluidic single cell separation technology: A technology for efficient separation and degradation of functional bacteria in single cell liquid phase

Bioresour Technol

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2024.04.08
Cycloalkane degradation by an uncultivated novel genus of Gammaproteobacteria derived from China’s marginal seas

J Hazard Mater

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2024.02.28
Culture-free identification of fast-growing cyanobacteria cells by Raman-activated gravity-driven encapsulation and sequencing

Synth Syst Biotechnol

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2023.11.11
Rapid Mycobacterium abscessus antimicrobial susceptibility testing based on antibiotic treatment response mapping via Raman Microspectroscopy

Ann Clin Microbiol Antimicrob

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2023.10.30
Optical-based microbubble for on-demand droplet release from static droplet array (SDA) for dispensing one droplet into one tube

Biosens Bioelectron

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2023.08.25
Single cell metabolic phenome and genome via the ramanome technology platform:Precision medicine of infectious diseases at the ultimate precision?

iLABMED

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2023.05.02
Single‐cell rapid identification, in situ viability and vitality profiling, and genome‐based source‐tracking for probiotics products

iMeta

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2023.04.17
An attempt to simultaneously quantify the polysaccharide, total lipid, protein and pigment in single Cyclotella cryptica cell by Raman spectroscopy

Biotechnol Biofuels Bioprod

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2023.04.08
Robust spontaneous Raman flow cytometry for single-cell metabolic phenome profiling via pDEP-DLD-RFC

Adv Sci (Weinh)

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2023.03.04
Artificial intelligence-assisted automatic and index-based microbial single-cell sorting system for One-Cell-One-TubemLife

mLife

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2022.12.04
Versatile, facile and low-cost single-cell isolation, culture and sequencing by optical tweezer-assisted pool-screening

Lab Chip

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2022.11.29
Single-cell Raman-activated sorting and cultivation (scRACS-Culture) for assessing and mining in situ phosphate-solubilizing microbes from nature

ISME Commun

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2022.10.30
Revealing CO2-fixing SAR11 bacteria in the ocean by Raman-based single-cell metabolic profiling and genomics

BioDesign Res

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2022.10.21
Single-cell Raman spectroscopy identifies Escherichia coli persisters and reveals their enhanced metabolic activities

Front Microbiol

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2022.08.04
Single-cell identification, drug susceptibility test, and whole-genome sequencing of Helicobacter pylori directly from gastric biopsy by clinical antimicrobial susceptibility test Ramanometry

Clin Chem

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2022.06.18
Single-cell Raman microspectroscopy-based assessment of three intracanal disinfectants' effect on Enterococcus faecalis

J Raman Spectro

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2022.05.02
Rapid, automated, and reliable antimicrobial susceptibility test from positive blood culture by CAST-R

mLife

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2022.04.18
Exploring a blue-light-sensing transcriptional factor to double the peak productivity of oil in Nannochloropsis oceanica

Nature Commun

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2022.03.29
Assessing efficacy of clinical disinfectants for pathogenic fungi by Single-cell Raman Microspectroscopy

Front Cell Infect Microbiol

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2022.02.23
Integrated addressable dynamic droplet array (aDDA) as sub-nanoliter reactors for high-coverage genome sequencing of single yeast cells

Small

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2021.07.23
Novel tigecycline resistance mechanisms in Acinetobacter baumannii mediated by mutations in adeS, rpoB and rrf

Emerg Microbes Infect

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2021.07.08
Culture-free identification and metabolic profiling of microalgal single cells via ensemble learning of ramanomes

Anal Chem

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2021.06.18
One-cell metabolic phenotyping and sequencing of soil microbiome by Raman-Activated Gravity-driven Encapsulation (RAGE)

mSystems

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2021.05.27
Genome engineering of Nannochloropsis with hundred-kilobase fragment deletions by Cas9 cleavages

Plant J

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2021.05.11
Intra-Ramanome Correlation Analysis unveils metabolite conversion network from an isogenic population of cells

mBio

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2021.05.01
Microbial metabolism and necromass mediated fertilization effect on soil organic carbon after long-term community incubation in different climates

ISME J

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2021.03.12
D2O-probed Raman microspectroscopy distinguishes metabolic dynamics of macromolecules in organellar anticancer drug response

Anal Chem

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2021.01.12
Positive dielectrophoresis–based Raman-activated droplet sorting for culture-free and label-free screening of enzyme function in vivo

Sci Adv

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2020.08.07
Phenome-genome profiling of single bacterial cell by Raman-Activated Gravity-Driven Encapsulation and Sequencing

Small

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2020.06.09
Rational optimization of Raman-activated cell ejection and sequencing for bacteria

Anal Chem

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2020.05.29
Ramanome technology platform for label-free screening and sorting of microbial cell factories at single-cell resolution

Biotechnol Adv

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2019.11.01
Smartphone-based rapid quantification of viable bacteria by single-cell microdroplet turbidity imaging

Analyst

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2018.07.09
Raman-activated cell sorting and metagenomic sequencing revealing carbon-fixing bacteria in the ocean

Environ Microbiol

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2018.06.01
Using Raman spectroscopy and chemometrics to identify the growth phase of Lactobacillus casei Zhang during batch culture at the single-cell level

Microb Cell Fact

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2017.12.23
Raman-Activated Droplet Sorting (RADS) for label-free high-throughput screening of microalgal single-cells

Anal Chem

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2017.11.21
Label-free, simultaneous quantification of starch, protein and triacylglycerol in single microalgal cells

Biotechnol Biofuels

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2017.11.17
Metabolic-activity-based assessment of antimicrobial effects by D2O-labeled single-cell Raman microspectroscopy

Anal Chem

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2017.03.10
Emerging Trends for Microbiome Analysis: From Single-Cell Functional Imaging to Microbiome Big Data

Engineering

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2017.02.01
Development of a facile droplet-based single-cell isolation platform for cultivation and genomic analysis in microorganisms

Sci Rep

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2017.01.23
Label-free, rapid and quantitative phenotyping of stress response in E. coli via ramanome

Sci Rep

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2016.10.19
Reverse and Multiple Stable Isotope Probing to Study Bacterial Metabolism and Interactions at the Single Cell Level

Anal Chem

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2016.10.04
Towards high-throughput microfluidic Raman-activated cell sorting

Analyst

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2015.09.21
Raman-activated cell sorting based on dielectrophoretic single-cell trap and release

Anal Chem

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2015.02.17
Precise quantitative addition of multiple reagents into droplets in sequence using glass fiber-induced droplet coalescence

Analyst

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2015.02.07
Tracking heavy water (D2O) incorporation for identifying and sorting active microbial cells

Proc Natl Acad Sci U S A

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2015.01.13
On-demand control of microfluidic flow via capillary-tuned solenoid microvalve suction

Lab Chip

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2014.12.21
Raman spectroscopy provides a rapid, non-invasive method for quantitation of starch in live, unicellular microalgae

Biotechnol J

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2014.12.01
Quantitative dynamics of triacylglycerol accumulation in microalgae populations at single-cell resolution revealed by Raman microspectroscopy

Biotechnol Biofuels

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2014.04.09
Raman activated cell ejection for isolation of single cells

Anal Chem

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2013.11.19
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